ykcC [2017-8-11 16:0:3]

similar to lipoteichoic acid glycosyltransferase

locus: BSU12890

pI: 8.01

mw: 37.22 kDa

protein length: 323 aa

gene length: 969 bp

function: decoration of lipoteichoic acid with galactose residues

essential: no

synonyms

Genomic Context

categories

• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
• [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

Gene

Coordinates: 1,356,447 → 1,357,418

The protein

Protein family

• GtrB subfamily (according to Swiss-Prot)

Paralogous protein(s)

• [protein|824E6AE2FFA3CBC9F90648F15178A00A6CC49E4C|CsbB], [protein|EF18470AD2B07755431534B52A8FCE6754FDBA9D|YkoT]

Structure

• [PDB|5EKP] (from Synechocystis sp., 47% identity) [pubmed|26729507]

[SW|Localization]

• cell membrane (heterogeneous) [Pubmed|16479537]

Expression and Regulation

Operons

• genes: [gene|7039FCF49F97FFEF37ED48D6F860E3873A5CF308|ykcB]-[gene|FD76A781162795EAF174B59C0A90D2ED3ACC0AB7|ykcC]
  description: [Pubmed|18175906]

  regulatory mechanism

  • [protein|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ]: activation, [Pubmed|20512483], in [regulon|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ regulon]
  • [protein|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|YrkP]: activation, [Pubmed|18175906], in [regulon|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|YrkP regulon]

Biological materials

Mutant

• MGNA-A739 (ykcC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/739 NBRP B. subtilis, Japan]

References

• 20512483,18175906,16479537,21630458,27185829,26729507